Green Life Healthy – Mesothelioma is cancer that attacks the mesothelium, the thin layer of tissue that surrounds most of the internal organs. Some of the organs that have the mesothelium, among others, the lungs (pleura), stomach (abdominal), heart (pericardial), and testicles (tunica vaginal). Cancer is quite aggressive, and many sufferers are not successfully treated, it’s the best article you must read about Mesothelioma Histology: Symptoms, Causes, and Treatment.

Mesothelioma most often affects the mesothelium of the lungs (called pleural mesothelioma) and the chest wall. Another type of mesothelioma is much less common is peritoneal mesothelioma, which attacks the mesothelium which the abdominal cavity. Mesothelioma is different from the conditions of benign mesothelioma in the chest which is also called the solitary fibrous tumor.

Causes of Mesothelioma

Mesothelioma Histology: Symptoms, Causes, and Treatment

Cancer that attacks the organs originated from cell mutations that cause growth becomes uncontrolled until later doubled. The experts could not determine the cause of this cell mutation. However, the interaction between lifestyle, hereditary conditions and environmental allegedly able to onset of cancer.
Although the cause is not yet known mesothelioma, the main risk factors of mesothelioma are asbestos. The disease is relatively rare before the commercial use of asbestos began. Asbestos is a mineral that is used as a material for making brakes, floor, roof, and insulation.

Mesothelioma Histology: Symptoms, Causes, and Treatment

Asbestos dust inhaled or ingested accumulates in the lungs and the stomach for a long time, usually around 20-50 years, before eventually develop into mesothelioma. Mesothelioma is diagnosed more often in men than women, and on a person over the age of 65 years.

Some other factors that can trigger this disease, namely:

  • Environmental whose land contains asbestos.
  • Staying in the area or live with someone who has a job related to Asbestos exposure also can stick on the skin and clothing so that it can carry asbestos into the home or another environment.
  • Have been proved to asbestos or have a family member suffering from mesothelioma.

Symptoms of Mesothelioma

Mesothelioma Histology: Symptoms, Causes, and Treatment

Mesothelioma Histology: Symptoms, Causes, and Treatment

Symptoms of mesothelioma can vary based on the location of the cancer cells are. Pericardial mesothelioma may cause chest pain and difficulty breathing, while mesothelioma is tunica vaginal will show symptoms such as swelling of the testicles.

Pleural mesothelioma has the following symptoms:

  • A cough with pain unbearable.
  • Shortness of breath due to the buildup of fluid in the chest.
  • Unusual lumps in the tissue under the skin of the chest.
  • Weight loss for no apparent reason.
  • Often suffers excessive fatigue.
  • Fever with sweating, especially at night.
  • Swollen fingertips.
  • Chest pain is felt below the rib cage.

Peritoneal mesothelioma has symptoms as follows:

  • Pain in the abdominal area.
  • There is a lump in the stomach tissue.
  • Swelling in the abdominal area.
  • Weight loss for no reason.
  • Diarrhea or constipation.

Given the symptoms of mesothelioma are not specific and can be associated with other conditions, then you should see your doctor so feel the symptoms above, especially if there is a history of exposure to asbestos.

Mesothelioma diagnosis

Mesothelioma Histology: Symptoms, Causes, and Treatment

Mesothelioma Histology: Symptoms, Causes, and Treatment

The examination will begin with the anamnesis of the symptoms suffered, personal and family medical records. Anamnesis is a communication conducted by doctors to patients directly as a way to get data about medical conditions and problems that are experienced by patients. Besides anamnesis, the doctor will perform a physical examination to check for lumps or signs are not normal.

Furthermore, the doctor may be instructed to be investigated as part of the diagnosis of the disease. Common examination for the diagnosis of mesothelioma, such as X-ray to check if there is any abnormality in the chest and a CT scan to check the area of the chest and abdomen.

Mesothelioma Histology: Symptoms, Causes, and Treatment

Biopsy or other tests may also be performed to determine what caused the disease symptoms appear. A biopsy is a laboratory examination of a small amount of tissue can be taken from diverse of the body, depending on the location of the disease. The tissue was then examined in a laboratory to determine what type of cells causing the disorder, as well as knowing the type of cancer they have. As for some types of biopsies may be recommended for the diagnosis of mesothelioma, namely:

  • Biopsy using a fine needle to withdraw a small sample of tissue or fluid from the chest or abdomen.
  • Laparoscopy – biopsy by making a small incision in the abdominal area to pick up the network. This procedure is assisted by a surgical instrument and a minuscule camera.
    Laparotomy – an open biopsy with how to dissect the stomach to take on the network that will be examined will be the presence of disease or other abnormalities.
  • Thoracoscopic or VATS (video-assisted thoracoscopic surgery) – Biopsy by making a small incision between the ribs to insert a camera and small surgical instrument into the chest cavity and take a small sample of tissue to be examined.
  • Thoracotomy – Biopsy with how to dissect an area between the ribs to inspect the area, whether there are indications of the disease and take tissue samples if necessary.

Once the diagnosis is established, the doctor will perform further tests on the patient’s body, such as imaging tests MRI and PET mapping, to determine the stage of disease and treatment steps that can be taken. There are four levels (stage) in pleural mesothelioma, while stage of deployment on other types of mesothelioma rarer still not known with certainty. Four stages of pleural mesothelioma consist of:

  • Stage I – the cancer is still localized conditions, only in one area in the chest lining.
  • Stage II – cancer has spread beyond the chest lining to the areas of the lung or diaphragm.
  • Stage III – cancer has spread to other parts in the chest or has invaded nearby lymph nodes. Some locations in the human lymph nodes is in the neck, armpits and around the groin,
  • Stage IV – cancer is an advanced stage that has spread to the entire chest or other body areas, such as brain and liver.

Mesothelioma Treatment

Mesothelioma Histology: Symptoms, Causes, and Treatment

Mesothelioma Histology: Symptoms, Causes, and Treatment

Several steps may be mesothelioma treatment recommended by a doctor. The selected treatment plan will depend on the condition of disease, stage of cancer, and the patient’s health in general. However, considering mesothelioma is cancer that is incurable, and generally can only be detected at an advanced stage, the treatment step is aimed to reduce the patient’s symptoms are felt.

While there are several treatment options for mesothelioma of the pleura and the abdomen, another case with pericardial mesothelioma and tunica vaginal is no cure because they are rarer. However, cancer is still in its early stages can be removed through surgery or the patient could still be in with other treatments to reduce symptoms.

Here are some steps that are performed mesothelioma treatment:


Mesothelioma Histology: Symptoms, Causes, and Treatment

Chemotherapy is a drug used to decrease or inhibit the growth of cancer. These drugs can spread throughout the body and can be used before surgery or after surgery. In the case of peritoneal mesothelioma, can be heated and supplied drugs directly into the abdominal cavity in order not to hurt healthy tissue in other body parts. This allows the dose of chemotherapy drugs administered in high doses.

Mesothelioma Histology: Symptoms, Causes, and Treatment

Chemotherapy is given before undergoing a surgical procedure to facilitate the operation because the cancer cells had diminished before finally lifted. Chemotherapy given after surgery will reduce the risk of cancer coming back.


Radiotherapy can be done after a surgical procedure to eradicate the remnants of cancer cells or reduce the symptoms of advanced cancer when surgery is not possible to do. In its application, this therapy uses high-energy emission levels, for example, X-ray and proton beams, which are focused on specific body areas.


Surgery is done to remove cancer that is still in the early stages of the disease, although in some cases still not managed to raise cancer cells completely. Surgery can also be done to reduce the symptoms of advanced cancer that has spread to other body parts with the aim of reducing the symptoms suffered. Here are some surgical options are carried out and its usefulness for patients with mesothelioma.

Mesothelioma Histology: Symptoms, Causes, and Treatment

The surgical procedure is to remove as many cancer cells can be eliminated from the patient’s body. This procedure allows the doctor to continue treatment with radiotherapy to reduce pain and prevent the buildup of excess fluid due to mesothelioma.

  • Operating procedures to lessen the buildup of fluid in the chest area that can interfere with breathing. The operation is performed by inserting a catheter tube into the chest to suck up the liquid. Doctors may also inject drugs to prevent a recurrence of fluid accumulation, also known as pleurodesis procedure.
  • Surgical removal of the tissue around the abdomen, ribs, or the lung who have been exposed to cancer cells to help reduce the symptoms and signs of mesothelioma.
  • Surgical removal of part of the lung affected following surrounding tissue to relieve symptoms in patients with pleural mesothelioma. This procedure is usually followed by high-dose radiotherapy.

Multimodality Therapy

This therapy is a combination of three or more treatment steps, such as surgery, postoperative chemotherapy (adjuvant chemotherapy), and radiation therapy to increase treatment success rate.

Alternative medicine

Alternative medicine has not been clinically proven to treat mesothelioma, but some treatments have shown a healthy development in patients with mesothelioma. Here are a related healing techniques.

  • Breathing exercises to control breathing when the patient begins to feel hard to breathe.
  • Relaxation exercises of the body, especially the respiratory muscles, patients can also make it easier to breathe lightly.
  • Sitting close to the fan facing faces difficulty breathing can reduce the sensation felt by the patient.
  • Acupuncture.

Discuss alternative treatment steps that you choose with your doctor before beginning to use it.

Mesothelioma Histology: Symptoms, Causes, and Treatment

Complementary or additional treatment may be recommended another doctor to reduce the symptoms of mesothelioma. Additional treatment, such as oxygen or certain drugs, can help the patient breathe more comfortably remember mesothelioma can cause pressure in the chest that can interfere with breathing.

Clinical Trials

Several clinical trials are available and informed in cancer patients, but the possibility of recovery is still not known for certain that it is important to consider carefully. Discuss with your doctor about clinical trials that exist and works for the condition of the patient. On the other hand, following a clinical trial will add an opportunity for physicians to find a cure for mesothelioma.

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Here are some of the clinical trials are being studied for mesothelioma conditions:

  • Biological therapy – using the immune system to fight cancer patient, also called immunotherapy.
  • Gene therapy – changing the genes contained in the cancer cells to stop this disease.
  • The therapy uses drugs to attack the abnormality/abnormalities that occur in cancer cells.

Complications Mesothelioma

Mesothelioma Histology: Symptoms, Causes, and Treatment

Here is a complication of pleural mesothelioma that has spread to the chest and cause depressed structure on the affected areas:

  • Pain in the chest area.
  • Pain caused by tension on the nerves and spinal cord.
  • Difficult to breathe.
  • Hard to swallow
  • Accumulation of fluid in the chest pressed the lungs and difficult process of Breath

Mesothelioma Prevention

The main precaution of mesothelioma is reducing contact with anything related to asbestos, the main cause of the development of mesothelioma. People who work or frequent exposure to asbestos is a group of high-risk people, such miners, factory workers, manufacturers/tool maker insulation, construction workers, and mechanics.

If you are part of one of the risk groups above, then you are obliged to comply with safety regulations set by the company. Sometimes it is better to leave asbestos in place than trying to move it without the help of experts, although both remain at risk of harm health. Find out, learn, and follow the instructions on the safe handling of asbestos in the environment around you. That’s all¬†Mesothelioma Histology: Symptoms, Causes, and Treatment.